Source: ALL
Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 5467
Gene Symbol: PPARD
PPARD 		0.330 Therapeutic disease CTD_human Ligand activation of peroxisome proliferator-activated receptor-beta/delta and inhibition of cyclooxygenase-2 enhances inhibition of skin tumorigenesis. 19748995 2010
Entrez Id: 5467
Gene Symbol: PPARD
PPARD 		0.330 Biomarker disease CTD_human Ligand activation of peroxisome proliferator-activated receptor-beta/delta and inhibition of cyclooxygenase-2 enhances inhibition of skin tumorigenesis. 19748995 2010
Entrez Id: 7517
Gene Symbol: XRCC3
XRCC3 		0.330 Biomarker disease CTD_human Single nucleotide polymorphisms in DNA repair genes and basal cell carcinoma of skin. 16501254 2006
Entrez Id: 7517
Gene Symbol: XRCC3
XRCC3 		0.330 Biomarker disease CTD_human A variant within the DNA repair gene XRCC3 is associated with the development of melanoma skin cancer. 11059748 2000
Entrez Id: 5727
Gene Symbol: PTCH1
PTCH1 		0.330 Biomarker disease CTD_human Missense mutations in SMOH in sporadic basal cell carcinomas of the skin and primitive neuroectodermal tumors of the central nervous system. 9581815 1998
Entrez Id: 360
Gene Symbol: AQP3
AQP3 		0.320 Biomarker disease CTD_human Critical role of aquaporin 3 on growth of human esophageal and oral squamous cell carcinoma. 21401805 2011
Entrez Id: 3091
Gene Symbol: HIF1A
HIF1A 		0.320 Biomarker disease CTD_human Hypoxia-inducible factor-1alpha suppresses squamous carcinogenic progression and epithelial-mesenchymal transition. 19276359 2009
Entrez Id: 7299
Gene Symbol: TYR
TYR 		0.320 Biomarker disease CTD_human ASIP and TYR pigmentation variants associate with cutaneous melanoma and basal cell carcinoma. 18488027 2008
Entrez Id: 1050
Gene Symbol: CEBPA
CEBPA 		0.310 Biomarker disease CTD_human C/EBPα expression is downregulated in human nonmelanoma skin cancers and inactivation of C/EBPα confers susceptibility to UVB-induced skin squamous cell carcinomas. 21346772 2011
Entrez Id: 338442
Gene Symbol: HCAR2
HCAR2 		0.310 Biomarker disease CTD_human Nicotinic acid receptor abnormalities in human skin cancer: implications for a role in epidermal differentiation. 21655214 2011
Entrez Id: 6648
Gene Symbol: SOD2
SOD2 		0.310 Therapeutic disease CTD_human Manganese superoxide dismutase: beyond life and death. 20454814 2012
Entrez Id: 3479
Gene Symbol: IGF1
IGF1 		0.310 Biomarker disease CTD_human Anticarcinogenic effect of quercetin by inhibition of insulin-like growth factor (IGF)-1 signaling in mouse skin cancer. 24353828 2013
Entrez Id: 6648
Gene Symbol: SOD2
SOD2 		0.310 Therapeutic disease CTD_human Overexpression of manganese superoxide dismutase suppresses tumor formation by modulation of activator protein-1 signaling in a multistage skin carcinogenesis model. 11507057 2001
Entrez Id: 4953
Gene Symbol: ODC1
ODC1 		0.310 Biomarker disease CTD_human Ability of m-chloroperoxybenzoic acid to induce the ornithine decarboxylase marker of skin tumor promotion and inhibition of this response by gallotannins, oligomeric proanthocyanidins, and their monomeric units in mouse epidermis in vivo. 7653998 1995
Entrez Id: 434
Gene Symbol: ASIP
ASIP 		0.310 Biomarker disease CTD_human ASIP and TYR pigmentation variants associate with cutaneous melanoma and basal cell carcinoma. 18488027 2008
Entrez Id: 2052
Gene Symbol: EPHX1
EPHX1 		0.310 Biomarker disease CTD_human In conclusion, GSTs, EPHX1, and XPD are potential genetic factors for arsenic-induced skin cancers. 26295053 2015
Entrez Id: 6667
Gene Symbol: SP1
SP1 		0.310 Biomarker disease CTD_human Manganese superoxide dismutase is a p53-regulated gene that switches cancers between early and advanced stages. 22009531 2011
Entrez Id: 7040
Gene Symbol: TGFB1
TGFB1 		0.310 Biomarker disease CTD_human Altered expression of transforming growth factor-beta 1 mRNA and protein in mouse skin carcinogenesis. 8148055 1994
Entrez Id: 6648
Gene Symbol: SOD2
SOD2 		0.310 Biomarker disease CTD_human Manganese superoxide dismutase is a p53-regulated gene that switches cancers between early and advanced stages. 22009531 2011
Entrez Id: 6648
Gene Symbol: SOD2
SOD2 		0.310 Biomarker disease CTD_human Overexpression of manganese superoxide dismutase suppresses tumor formation by modulation of activator protein-1 signaling in a multistage skin carcinogenesis model. 11507057 2001
Entrez Id: 25913
Gene Symbol: POT1
POT1 		0.310 Biomarker disease CTD_human POT1 loss-of-function variants predispose to familial melanoma. 24686849 2014
Entrez Id: 6648
Gene Symbol: SOD2
SOD2 		0.310 Biomarker disease CTD_human Manganese superoxide dismutase: beyond life and death. 20454814 2012
Entrez Id: 4318
Gene Symbol: MMP9
MMP9 		0.310 Biomarker disease CTD_human Arsenic-induced malignant transformation of human keratinocytes: involvement of Nrf2. 18572023 2008
Entrez Id: 207
Gene Symbol: AKT1
AKT1 		0.310 Biomarker disease CTD_human The PI3-K/AKT pathway is known to have a role in both skin cancer development and resistance to therapeutic drugs. 21351258 2010
Entrez Id: 6648
Gene Symbol: SOD2
SOD2 		0.310 Therapeutic disease CTD_human Manganese superoxide dismutase is a p53-regulated gene that switches cancers between early and advanced stages. 22009531 2011